Search on: RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I 
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Descriptor English:   Receptors, Tumor Necrosis Factor, Type I 
Descriptor Spanish:   Receptores Tipo I de Factores de Necrosis Tumoral 
Descriptor Portuguese:   Receptores Tipo I de Fatores de Necrose Tumoral 
Synonyms English:   CD 120a Antigen
CD120a Antigen
TNFR p60
TNFR-I
TNFR1
TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A)
TNFRSF1A Receptor
Tumor Necrosis Factor Receptor 1A
Tumor Necrosis Factor Receptor Type 1
120a Antigen, CD
Antigen, CD 120a
Antigen, CD120a
Receptor, TNFRSF1A
Antigens, CD120a
CD120a Antigens
Receptors, Tumor Necrosis Factor, Member 1A
Tumor Necrosis Factor Receptor Superfamily, Member 1A
Tumor Necrosis Factor Receptor Type I  
Tree Number:   D12.776.543.750.690.750
D12.776.543.750.705.852.760.597
Definition English:   A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. 
History Note English:   2005(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38769 
Unique Identifier:   D047888 

Occurrence in VHL: 		 

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